Reverse peptide of indolicidin (Rev4), a 13-residue peptide based on the sequence of indolicidin1.Indolicidin, a member of the cathelicidin protein family, is a 13-residue cationic, antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils2. The synthetic peptide Rev4 has been shown to possess both strong antimicrobial and protease inhibitory activities in vitro.
1. Xing H. et al., Planta, 223 (5),1024-32 (2005) 2. Ösapay, K. et al. J. Biol. Chem. 275, 12017 (2000) 3. Li Q. et al., Peptides 23(1),1-6 (2002)
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Arg - Arg - Trp - Pro - Trp - Trp - Pro - Trp - Lys - Trp - Pro - Leu - Ile - OH